Hospital Instructions for Safe Infant Formula Preparation, Storage, and Use

  • Powdered formulas are not sterile. “To minimize the risk of infection, powdered formulas are not recommended for use in premature or immunocompromised infants unless no appropriate nutritional alternative is available, and then only with strict medical supervision and careful preparation, storage and use.”1

    Preparation and Use Instructions1,2
    • Follow hospital procedures carefully
    • Check label against individual patient’s feeding order (confirm product identity and dilution)
    • Wash and dry hands and clean work area thoroughly with an antibacterial sanitizing solution that is appropriate for food contact surfaces.
    • Ensure container integrity
    • Use only sterilized containers and measuring equipment
    • Avoid touch contamination of formula at each step
    • Visually inspect the formula (if anything looks unusual, set it aside and contact your Mead Johnson representative)
    • When preparing powdered or concentrated liquid formulas, chilled, sterilized water is recommended
    • Do not use a blender to reconstitute powdered formula
    • Do not store in formula warmer or use microwave oven to warm formula

    Storage Instructions for Prepared Formula
    Refrigeration
    • Dedicated refrigerators recommended.
    • Store at 2-4°C (35-40° F) no longer than 24 hours

    Room Temperature
    • Should be fed immediately, but hold no longer than a total of 2 hours before feeding
    • If bottle is warmed, discard after 1 hour

    After Feeding Begins
    • Feed within 1 hour or discard
    • Do not refrigerate for later feedings

    Tube-feeding Hangtime*† for Prepared Formula From: Neonates or
    Immunocompromised
    Infants/Children
    Infants and Children
    with Healthy Immune
    Systems
    Ready-To-Feed unaltered infant formula (commercially sterile) 4 hrs 8hrs
    Concentrated liquid formulas (commercially sterile)
    Powdered formulas (not sterile)
    4 hrs 4hrs
    Powder added to liquid formula or expressed breast milk3 4 hrs 4hrs
    Liquid (commercially sterile) added to expressed breast milk 4 hrs 4hrs

    Failure to follow these instructions could result in severe harm.
    * Adapted from: Robbins and Meyers, p.1002

    † For reservoir and tube-change guidelines, refer to the ADA publication, Infant Feedings: Guidelines for Preparation of Formula and Breastmilk in Health Care Facilities. 2004.

    1.International Formula Council. Infant Feeding: Safety Issues for Health Care Professionals. Atlanta, GA: International Formula Council; 2004:4.
    2. Robbins ST, Meyers R, eds. Infant Feedings: Guidelines for Preparation of Human Milk and Formula in Health Care Facilities. Chicago, Ill: American Dietetic Association; 2011.
    3. Telang S, Berseth CL, Ferguson PW, et al. Fortifying fresh human milk with commercial powdered human milk fortifiers does not affect bacterial growth during 6 hours at room temperature. J Am Diet Assoc. 2005;105:1567-1572.

    The American Dietetic Association is now known as the Academy of Nutrition and Dietetics.

  • Intended for Canadian Healthcare Professionals Only.
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    All Rights Reserved.